Spironolactone vs. Duac


We compare the side effects and drug effectiveness of Spironolactone and Duac. The study is created by eHealthMe based on reports of 80,761 people who take Spironolactone and Duac, and is updated regularly.

What's eHealthMe?

eHealthMe is a health data analysis company based in Mountain View, California. eHealthMe monitors and analyzes the outcomes of drugs and supplements that are currently on the market. The results are readily available to health care professionals and consumers. Choose a tool to use eHealthMe.

eHealthMe has released original studies on market drugs and worked with leading universities and institutions such as IBM, London Health Science Centre, Mayo Clinic, Northwestern University and VA. eHealthMe studies have now been referenced in over 500 peer-reviewed medical publications.

How the study uses the data?

The study is based on spironolactone and benzoyl peroxide; clindamycin phosphate (the active ingredients of Spironolactone and Duac, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered.

What is Spironolactone?

Spironolactone has active ingredients of spironolactone. It is often used in acne. Check the latest outcomes from 49,299 Spironolactone users, or browse all drugs.

What is Duac?

Duac has active ingredients of benzoyl peroxide; clindamycin phosphate. It is often used in acne. Check the latest outcomes from 424 Duac users, or browse all drugs.

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.

Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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On eHealthMe, we believe health data should work with individual experience to improve drug outcomes. With our Ginger Health app, you can get one-to-one mobile support from people like you. Patients and caregivers can get paid with their health care experience as a Care Guide. Learn more about Care Guides.

On Mar, 22, 2019

80,761 people who take Spironolactone and Duac are studied.

Number of reports submitted per year:

Spironolactone vs Duac drug comparison reports.

Drugs in this study:

  • Spironolactone (spironolactone)
  • Duac (benzoyl peroxide; clindamycin phosphate)

Most common side effects:

  1. Erythema (redness of the skin)
  2. Drug Ineffective
  3. Anxiety
  4. Pain
  5. Pulmonary Embolism (blockage of the main artery of the lung)
  6. Pruritus (severe itching of the skin)
  7. Rash
  8. Nausea (feeling of having an urge to vomit)
  9. Depression
  10. Deep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  1. Dyspnoea (difficult or laboured respiration)
  2. Nausea (feeling of having an urge to vomit)
  3. Fatigue (feeling of tiredness)
  4. Diarrhoea
  5. Hyperkalaemia (damage to or disease of the kidney)
  6. Renal Failure Acute (rapid kidney dysfunction)
  7. Vomiting
  8. Asthenia (weakness)
  9. Anaemia (lack of blood)
  10. Hypotension (abnormally low blood pressure)

Most common side effects experienced by people in long term use:

  1. Depression
  2. Colitis Ulcerative (inflammation of colon with ulcer)
  3. Suicidal Ideation
  4. Inflammatory Bowel Disease
  5. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract)
  6. Anxiety
  7. Blood Cholesterol Increased
  8. Emotional Distress
  9. Deep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  10. Diarrhoea
  1. Hyperkalaemia (damage to or disease of the kidney)
  2. Renal Failure Acute (rapid kidney dysfunction)
  3. Dehydration (dryness resulting from the removal of water)
  4. Renal Failure (kidney dysfunction)
  5. Pain
  6. Vomiting
  7. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  8. Cardiac Failure
  9. Dyspnoea (difficult or laboured respiration)
  10. Renal Impairment (severely reduced kidney function)

Drug effectiveness:

  • not at all: 4.44 %
  • somewhat: 26.67 %
  • moderate: 31.11 %
  • high: 24.44 %
  • very high: 13.33 %
  • not at all: 5.26 %
  • somewhat: 22.64 %
  • moderate: 31.64 %
  • high: 27.71 %
  • very high: 12.75 %

Do you take Spironolactone or Duac?

You are not alone:

Related studies:

Mobile peer-to-peer support:

Ginger Health (developed by eHealthMe) has millions of focused support groups to join: each group for one drug side effect, symptom, drug or condition. You can also follow Care Guides who "have been there" to help you meet care goals and improve day-to-day life.

Recent publications that referenced eHealthMe studies

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.