Epiduo vs Absorica - from FDA reports

This is a side effect comparison of Epiduo and Absorica. The study is created by eHealthMe based on reports from FDA, and is updated regularly.

How to use this study: bring a copy to your health teams to ensure drug risks and benefits are fully discussed and understood.

On Feb, 11, 2019

48,788 people who take Epiduo and Absorica are studied.

Number of reports submitted per year:

Epiduo vs Absorica drug comparison reports.

Drugs in this study:

  • Absorica (isotretinoin)
  • Epiduo (adapalene; benzoyl peroxide)

eHealthMe real world results:

Most common side effects:

  1. Inflammatory Bowel Disease
  2. Depression
  3. Colitis Ulcerative (inflammation of colon with ulcer)
  4. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract)
  5. Irritable Bowel Syndrome
  6. Anxiety
  7. Colitis (inflammation of colon)
  8. Dry Skin
  9. Suicidal Ideation
  10. Headache (pain in head)
  1. Erythema (redness of the skin)
  2. Dry Skin
  3. Skin Burning Sensation
  4. Drug Ineffective
  5. Skin Exfoliation (removal of the oldest dead skin cells)
  6. Pruritus (severe itching of the skin)
  7. Swelling Face
  8. Pain Of Skin
  9. Skin Irritation
  10. Rash

Most common side effects experienced by people in long term use:

  1. Inflammatory Bowel Disease
  2. Colitis Ulcerative (inflammation of colon with ulcer)
  3. Depression
  4. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract)
  5. Irritable Bowel Syndrome
  6. Intestinal Obstruction
  7. Injury
  8. Anxiety
  9. Intestinal Haemorrhage (bleeding from intestine)
  10. Gastrointestinal Injury (injury to gastrointestinal tract)
  1. Drug Ineffective
  2. Pruritus (severe itching of the skin)
  3. Erythema (redness of the skin)
  4. Dry Skin
  5. Rebound Effect (take-back effect)
  6. Emotional Distress
  7. Drug Effect Decreased
  8. Pain
  9. Pre-Existing Condition Improved
  10. Therapeutic Response Unexpected

What are the drugs?

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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