Aspirin vs Simvastatin - from FDA reports

This is a side effect comparison of Aspirin and Simvastatin. The study is created by eHealthMe based on reports from FDA, and is updated regularly.

How to use this study: bring a copy to your health teams to ensure drug risks and benefits are fully discussed and understood.

On Feb, 11, 2019

562,748 people who take Aspirin and Simvastatin are studied.

Number of reports submitted per year:

Aspirin vs Simvastatin drug comparison reports.

Drugs in this study:

  • Simvastatin (simvastatin)
  • Aspirin (aspirin)

eHealthMe real world results:

Most common side effects:

  1. Dyspnoea (difficult or laboured respiration)
  2. Nausea (feeling of having an urge to vomit)
  3. Fatigue (feeling of tiredness)
  4. Pain
  5. Drug Ineffective
  6. Diarrhoea
  7. Dizziness
  8. Myalgia (muscle pain)
  9. Asthenia (weakness)
  10. Fall
  1. Dyspnoea (difficult or laboured respiration)
  2. Nausea (feeling of having an urge to vomit)
  3. Fatigue (feeling of tiredness)
  4. Dizziness
  5. Diarrhoea
  6. Pain
  7. Drug Ineffective
  8. Asthenia (weakness)
  9. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract)
  10. Headache (pain in head)

Most common side effects experienced by people in long term use:

  1. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  2. Myalgia (muscle pain)
  3. Fatigue (feeling of tiredness)
  4. Pain In Extremity
  5. Muscular Weakness (muscle weakness)
  6. Blood Creatine Phosphokinase Increased
  7. Arthralgia (joint pain)
  8. Asthenia (weakness)
  9. Renal Failure Acute (rapid kidney dysfunction)
  10. Pain
  1. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract)
  2. Anaemia (lack of blood)
  3. Haemoglobin Decreased
  4. Melaena (the passage of black, tarry stools)
  5. Dizziness
  6. Dyspnoea (difficult or laboured respiration)
  7. Diarrhoea
  8. Cerebral Haemorrhage (bleeding within the brain)
  9. Haematemesis (vomiting of blood)
  10. Death

What are the drugs?

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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