Arava vs. Cimzia


We compare the side effects and drug effectiveness of Arava and Cimzia. The study is created by eHealthMe based on reports of 75,299 people who take Arava and Cimzia, and is updated regularly.

What's eHealthMe?

eHealthMe is a health data analysis company based in Mountain View, California. eHealthMe monitors and analyzes the outcomes of drugs and supplements that are currently on the market. The results are readily available to health care professionals and consumers.

eHealthMe has released original studies on market drugs and worked with leading universities and institutions such as IBM, London Health Science Centre, Mayo Clinic, Northwestern University and VA. eHealthMe studies have now been referenced in over 500 peer-reviewed medical publications.

How we gather our data?

Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). This information is aggregated and used to produce personalized reports that patients can reference.

The information that eHealthMe collects includes:

  • Side effects (including severity and how people recover from them)
  • Associated conditions or symptoms
  • Drug effectiveness
  • Demographic data regarding drug use

How the study uses the data?

The study is based on leflunomide and certolizumab pegol (the active ingredients of Arava and Cimzia, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered.

What is Arava?

Arava has active ingredients of leflunomide. It is often used in rheumatoid arthritis. (latest outcomes from Arava 26,030 users)

What is Cimzia?

Cimzia has active ingredients of certolizumab pegol. It is often used in rheumatoid arthritis. (latest outcomes from Cimzia 25,706 users)

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.

On Mar, 14, 2019

75,299 people who take Arava and Cimzia are studied.

Number of reports submitted per year:

Arava vs Cimzia drug comparison reports.

Drugs in this study:

  • Arava (leflunomide)
  • Cimzia (certolizumab pegol)

eHealthMe real world results:

Most common side effects:

  1. Drug Ineffective
  2. Fatigue (feeling of tiredness)
  3. Pneumonia
  4. Abdominal Pain
  5. Arthralgia (joint pain)
  6. Diarrhoea
  7. Pain
  8. Nausea (feeling of having an urge to vomit)
  9. Pyrexia (fever)
  10. Rash
  1. Drug Ineffective
  2. Arthralgia (joint pain)
  3. Pain
  4. Diarrhoea
  5. Nausea (feeling of having an urge to vomit)
  6. Fatigue (feeling of tiredness)
  7. Dyspnoea (difficult or laboured respiration)
  8. Headache (pain in head)
  9. Pneumonia
  10. Pyrexia (fever)

Most common side effects experienced by people in long term use:

  1. Pneumonia
  2. Drug Ineffective
  3. Urinary Tract Infection
  4. Sinusitis (inflammation of sinus)
  5. Herpes Zoster
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Pyrexia (fever)
  8. Diarrhoea
  9. Arthralgia (joint pain)
  10. Nausea (feeling of having an urge to vomit)
  1. Drug Ineffective
  2. Drug Exposure During Pregnancy
  3. Diarrhoea
  4. Pneumonia
  5. Pyrexia (fever)
  6. Nausea (feeling of having an urge to vomit)
  7. Alanine Aminotransferase Increased
  8. Hypertension (high blood pressure)
  9. Aspartate Aminotransferase Increased
  10. Vomiting

Drug effectiveness:

  • not at all: 9.38 %
  • somewhat: 27.34 %
  • moderate: 34.38 %
  • high: 24.22 %
  • very high: 4.69 %
  • not at all: 7.29 %
  • somewhat: 30.32 %
  • moderate: 31.78 %
  • high: 23.62 %
  • very high: 7.0 %

Do you take Arava or Cimzia?

You are not alone:

Related studies:

Compare Arava with similar drugs
Compare Cimzia with similar drugs

Recent updates

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WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.