Aczone vs. Adapalene


We compare the side effects and drug effectiveness of Aczone and Adapalene. The study is created by eHealthMe based on reports of 7,254 people who take Aczone and Adapalene, and is updated regularly.

What's eHealthMe?

eHealthMe is a health data analysis company based in Mountain View, California. eHealthMe monitors and analyzes the outcomes of drugs and supplements that are currently on the market. The results are readily available to health care professionals and consumers. Choose a tool to use eHealthMe.

eHealthMe has released original studies on market drugs and worked with leading universities and institutions such as IBM, London Health Science Centre, Mayo Clinic, Northwestern University and VA. eHealthMe studies have now been referenced in over 500 peer-reviewed medical publications.

How the study uses the data?

The study is based on dapsone and adapalene (the active ingredients of Aczone and Adapalene, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered.

What is Aczone?

Aczone has active ingredients of dapsone. It is often used in acne. Check the latest outcomes from 593 Aczone users, or browse all drugs.

What is Adapalene?

Adapalene has active ingredients of adapalene. It is often used in acne. Check the latest outcomes from 306 Adapalene users, or browse all drugs.

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.

Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

Data + Experience to manage medications:

On eHealthMe, we believe health data should work with individual experience to improve drug outcomes. With our Ginger Health app, you can get one-to-one mobile support from people like you. Patients and caregivers can get paid with their health care experience as a Care Guide. Learn more about Care Guides.

On Apr, 01, 2019

7,254 people who take Aczone and Adapalene are studied.

Number of reports submitted per year:

Aczone vs Adapalene drug comparison reports.

Drugs in this study:

  • Adapalene (adapalene)
  • Aczone (dapsone)

Most common side effects:

  1. Depression
  2. Anxiety
  3. Pain
  4. Dry Skin
  5. Drug Ineffective
  6. Headache (pain in head)
  7. Dyspnoea (difficult or laboured respiration)
  8. Nausea (feeling of having an urge to vomit)
  9. Inflammatory Bowel Disease
  10. Erythema (redness of the skin)
  1. Pyrexia (fever)
  2. Anaemia (lack of blood)
  3. Nausea (feeling of having an urge to vomit)
  4. Diarrhoea
  5. Dyspnoea (difficult or laboured respiration)
  6. Fatigue (feeling of tiredness)
  7. Pneumonia
  8. Vomiting
  9. Drug Ineffective
  10. Headache (pain in head)

Most common side effects experienced by people in long term use:

  1. Anxiety
  2. Chest Pain
  3. Depression
  4. Pain
  5. Insomnia (sleeplessness)
  6. Dry Skin
  7. Cholecystitis Chronic (long lasting infection of gallbladder)
  8. Asthma
  9. Alopecia (absence of hair from areas of the body)
  10. Headache (pain in head)
  1. Bicytopenia (two parameters from the full blood count are low, the term bicytopenia can be used)
  2. Anaemia (lack of blood)
  3. Pyrexia (fever)
  4. Anxiety
  5. Diarrhoea
  6. Dehydration (dryness resulting from the removal of water)
  7. Toxoplasmosis (a parasitic disease caused by the protozoan toxoplasma gondii)
  8. Encephalopathy (functioning of the brain is affected by some agent or condition)
  9. Depression
  10. Death

Drug effectiveness:

  • not at all: 4.76 %
  • somewhat: 42.86 %
  • moderate: 38.1 %
  • high: 4.76 %
  • very high: 9.52 %
  • not at all: 6.36 %
  • somewhat: 22.73 %
  • moderate: 25.45 %
  • high: 28.18 %
  • very high: 17.27 %

Do you take Aczone or Adapalene?

You are not alone:

Related publications that referenced our studies

Related studies:

Mobile peer-to-peer support:

Ginger Health (developed by eHealthMe) has millions of focused support groups to join: each group for one drug side effect, symptom, drug or condition. You can also follow Care Guides who "have been there" to help you meet care goals and improve day-to-day life.

Recent publications that referenced eHealthMe studies

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.